Editorial: Therapeutic potential of plant-derived metabolites in spinal or sciatic injury-induced neuropathic pain
نویسندگان
چکیده
EDITORIAL article Front. Pharmacol., 17 July 2023Sec. Ethnopharmacology Volume 14 - 2023 | https://doi.org/10.3389/fphar.2023.1251613
منابع مشابه
Analgesic effect of α-terpineol on neuropathic pain induced by chronic constriction injury in rat sciatic nerve: Involvement of spinal microglial cells and inflammatory cytokines
Objective(s): Neuropathic pain is a prevalent and debilitating neurological disorder. Ample evidence indicates that microglial cells and inflammatory cytokines are involved in the pathogenesis of neuropathic pain. Alpha-terpineol is a monoterpenoid alcohol with inhibitory effect on inflammatory cytokines. The main purpose of this study was to evaluate the effect of α-t...
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متن کاملNeuropathic pain in spinal cord injury.
BACKGROUND Several studies have described pain prevalence, risk factors, pain and medical variables in spinal cord injury (SCI) populations. In this study on traumatic SCI in Turkey, we surveyed the neuropathic pain experiences during in-patient rehabilitation and defined the relationships between neuropathic pain and demographic and SCI characteristics of patients. OBJECTIVES To survey the n...
متن کاملEffect of coenzyme Q10 on neuropathic pain threshold resulting from spinal cord injury in male rats
Introduction: Coenzyme Q10 is a powerful antioxidant that has the ability to reduce the damage caused by oxidative stress and is predominantly found in the inner mitochondrial membrane. This study was conducted to determine the effect of coenzyme Q10 on neuropathic pain in an animal model of spinal cord injury. Methods: In order to induce neuropathic pain, thoracic segments of the spinal cor...
متن کاملAnalgesic Effect of Bumetanide on Neuropathic Pain in Patients With Spinal Cord Injury
Objectives: The current study evaluated the analgesic effects of bumetanide as an adjunctive in the management of neuropathic pain following spinal cord injury (SCI). The peripheral expression of Na-K-Cl cotransporter-1 (NKCC1) and K-Cl cotransporter-2 (KCC2) genes in polymorphonuclear lymphocytes (PMLs) was assessed as a possible biomarker indicating central mechanisms underlying the observed ...
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ژورنال
عنوان ژورنال: Frontiers in Pharmacology
سال: 2023
ISSN: ['1663-9812']
DOI: https://doi.org/10.3389/fphar.2023.1251613